The very unusual guest - the first beaver to ever be treated by the team at the animal welfare charity's West Hatch centre near Taunton - had been rescued near Exmouth after being found stuck in the mud.
RSPCA West Hatch's wildlife vet, Dr David Couper, said:
The beaver came in totally collapsed, I think mostly from exhaustion and stress, but there was the possibility of salt water poisoning as it is assumed it had been in the sea for a length of time.
Thankfully, with supportive care in terms of fluids and warmth, the beaver picked up markedly over the next couple of days.
The beaver was initially released into a temporary enclosure.
Once the beaver was fully fit, the RSPCA team worked closely with Devon Wildlife Trust and Natural England to get ready for the beaver to be released on the River Otter in Devon.
After careful transportation from the wildlife centre, the beaver was initially released into a temporary enclosure on the river before spending two weeks being carefully monitored by the team from Devon Wildlife Trust to ensure the beaver was finally ready for the temporary enclosure to be removed.
Steve Hussey, from Devon Wildlife Trust, said:
"We want to thank the efforts of this beaver's rescuers, and also the wonderful work of the RSPCA in giving it a safe and secure home during the recuperation.
"We think this beaver was a juvenile animal, probably looking to find a new territory in which to set up home. Somewhere along the line it just took a wrong turn.
"We've now returned the beaver to a quiet section of the River Otter and our last observations of it showed the animal to be doing well.
"In August 2020 we received the good news that Defra had given the beaver population living wild on the River Otter leave to stay permanently. We are now awaiting Defra's decision as to whether further reintroductions of this once-native animal species can take place elsewhere in England."